Is exhaled nitric oxide a marker of air pollution effect?
نویسندگان
چکیده
Affiliations: Epidemiology of Allergic and Respiratory Diseases Dept (EPAR), Sorbonne Universités, UPMC Univ Paris 06, INSERM, Pierre Louis Institute of Epidemiology and Public Health (IPLESP UMRS 1136), Saint-Antoine Medical School, Paris, France. Université Paris Descartes, Hôpital Cochin – Paris Centre, Assistance Publique Hôpitaux de Paris, Laboratoire de Physiologie Respiratoire, UPRES-EA 2511, Paris, France.
منابع مشابه
Increased exhaled nitric oxide on days with high outdoor air pollution is of endogenous origin.
The aim of this study was to assess the effect of outdoor air pollution on exhaled levels of endogenously released nitric oxide. To exclude bias from exogenous NO in the recovered exhaled air (residual NO or NO in dead volume) an experimental design was used that sampled NO of endogenous origin only. The validity of the presented experimental design was established in experiments where subjects...
متن کاملComparison of the Fractional Exhaled Nitric Oxide Levels in Adolescents at Three Schools Located Three Different Distances from a Large Steel Mill
Objectives. Exposure to ambient metals and air pollutants in urban environments has been associated with impaired lung health and inflammation in the lungs. Fractional exhaled nitric oxide (FeNO) is a reliable marker of airway inflammation. In this study, we aimed to compare the FeNO levels of three schools that have different distances from iron and steel industry zone for assessing the effect...
متن کاملFlow-dependency of exhaled nitric oxide in children with asthma and cystic fibrosis.
The concentration of nitric oxide in exhaled air, a marker of airway inflammation, depends critically on the flow of exhalation. Therefore, the aim of this study was to determine the effect of varying the flow on end-expiratory NO concentration and NO output in children with asthma or cystic fibrosis (CF) and in healthy children. Nineteen children with stable asthma, 10 with CF, and 20 healthy ...
متن کاملExhaled NO: Determinants and Clinical Application in Children With Allergic Airway Disease
Nitric oxide (NO) is endogenously released in the airways, and the fractional concentration of NO in exhaled breath (FeNO) is now recognized as a surrogate marker of eosinophilic airway inflammation that can be measured using a noninvasive technique suitable for young children. Although FeNO levels are affected by several factors, the most important clinical determinants of increased FeNO level...
متن کاملClinical aspects of exhaled nitric oxide.
There has been intense research into the role nitric oxide (NO) plays in physiological and pathological mechanisms and its clinical significance in respiratory medicine. Elevated levels of exhaled levels of exhaled NO in asthma and other inflammatory lung diseases lead to many studies examining NO as potential markers of airway inflammation, enabling repeated noninvasive and standardized monito...
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ورودعنوان ژورنال:
- The European respiratory journal
دوره 47 5 شماره
صفحات -
تاریخ انتشار 2016